凯恩格生物科技（宜昌）有限公司
Saccharomyces boulardii is a yeast probiotic. Because of its unique biological function, it is often used as probiotics in medicine and feed production. In medicine, it has good clinical effects in the treatment of antibiotic related diarrhea, recurrent Clostridium difficile disease, rotavirus diarrhea and inflammatory bowel disease. In feed application, Saccharomyces cerevisiae var boulardii has a good effect on diarrhea caused by microbial infection and biotoxin. Saccharomyces boulardii is not only effective in preventing diarrhea in monogastric animals, but also effective in improving ruminant intestinal health, reducing diarrhea rate and improving immune function.
Case 1: effect on immune function
Experimental location: at the Dairy Research and Technology Centre (DRTC) of the University of Alberta
Experimental animals: A total of 20 Holstein bull calves born with a birth BW between 35 and 55 kg
Experimental period: From May to August 2018
Experimental grouping:
Experimental results:
The concentration of sIgA in the ileum and colon in 1-wk-old SCB calves were higher than in CON calves (P < 0.01).
Case 2: effect on diarrhea and loose stool
Experimental location: in a commercial milk-fed veal facility in Cambridge, Ontario, Canada
Experimental animals: A total of 84 Holstein bull calves with an age of 6 ± 3d (± SD)
Experimental period: March, 2017
Experimental grouping:
Experimental results:
The SCB supplementation specifically decreased the fecal score of the calves at wk 1, 2, and 4 in comparison with the CON group.
The SCB supplementation specifically decreased the diarrhea cases of the calves at wk 1 and 2 in comparison with the CON group.
Other cases
Fomenky, B (2016), Pais P, (2020), Lee JS (2019), Dong Yunhai (2019) and many other scholars have confirmed that Saccharomyces boulardii (CNCM I-1079) is beneficial in regulating the structure of gastrointestinal flora, improving intestinal health, improving immunity, and improving production performance, especially in the prevention of diarrhea in young animals.
References
[1] Pais P , Almeida V , Ylmaz M , et al. Saccharomyces boulardii: What Makes It Tick as Successful Probiotic?[J]. Journal of Fungi—Open Access Mycology Journal, 2020, 6(2):78.
[2]邵亚群,胡骏鹏,王之盛,等.酵母细胞壁对犊牛生长性能、营养物质表观消化率和血清免疫指标的影响[J].动物营养学报, 2019, 031(001):378-387.
[3]董运海,张海波,陈智仙,等.布拉氏酵母对抗生素相关腹泻作用的研究进展[J].国外医药(抗生素分册), 2019, 40(001):50-55.
[4] Lee J S , Kacem N , Kim W S , et al. Effect of Saccharomyces boulardii Supplementation on Performance and Physiological Traits of Holstein Calves under Heat Stress Conditions[J]. Animals : an Open Access Journal from MDPI, 2019, 9(8).
[5]Fomenky, B, Chiquette, et al. 0462 Saccharomyces cerevisiae boulardii improves acute phase response and phagocytosis during weaning in dairy calves[J]. Journal of Animal Science, 2016, 94(suppl_5):220–221.
